As of August 18, 2025, the Cancer Genetics and Genomics Laboratory (CGL) at BC Cancer is offering a new FISH probe – MAML2 FISH for the indication of mucoepidermoid carcinoma (MEC) using a break-apart probe. This FISH assay will detect any rearrangement of MAML2, regardless of the fusion partner. Further details can be found here.
The specimen requirements for this new FISH probe are the same as other solid tumours and can be ordered by sending the following to CGL:
- A completed CGL Cytogenetics Solid Tumour Testing requisition form.
- An H&E stained slide with the tumour region circled, and the estimated % tumour content written in the Tumour Content field of the requisition.
NOTE: A minimum of 10% tumour and at least 200 nuclei is required. - Specimen block and two unstained slides.
- See our FFPE Guidelines for additional details.